In January 2000, when Primal Scream performed "Pills" live on "Later... with Jools Holland," the band was on the cusp of a significant phase in their career. This performance came shortly after the release of their album "Give Out But Don’t Give Up," which was launched in 1994 and showcased a departure from their earlier sound, embracing a classic rock and roll aesthetic. By this point, the band had established themselves as influential figures in the alternative rock scene, known for their eclectic style that blended rock, dance, and psychedelic influences. The live rendition of "Pills" highlights their energetic performance style, while the song itself reflects the band's exploration of themes related to substance use and culture. Following this period, Primal Scream would continue to evolve, with their next album, "XTRMNTR," released in 2000, marking a return to a more electronic and punk-inspired sound.